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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
16/02/2016 |
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Data da última atualização: |
03/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
KIM, E. S.; SONSTEGARD, T. S.; SILVA, M. V. G. B.; GASBARRE, L. C.; TASSEL, C. P. V. |
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Afiliação: |
Eui-Soo Kim; Tad S. Sonstegard; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; Louis C. Gasbarre; Curtis P. Van Tassell. |
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Título: |
Genome-wide scan of gastrointestinal nematode resistance in closed Angus population selected for minimized influence of MHC. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
PLoS One, v. 10, n. 3, : e0119380, 2015. |
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Páginas: |
18 p. |
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Idioma: |
Inglês |
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Conteúdo: |
Genetic markers associated with parasite indicator traits are ideal targets for study of marker assisted selection aimed at controlling infections that reduce herd use of anthelminthics. For this study, we collected gastrointestinal (GI) nematode fecal egg count (FEC) data from post-weaning animals of an Angus resource population challenged to a 26 week natural exposure on pasture. In all, data from 487 animals was collected over a 16 year period between 1992 and 2007, most of which were selected for a specific DRB1 allele to reduce the influence of potential allelic variant effects of the MHC locus. A genome-wide association study (GWAS) based on BovineSNP50 genotypes revealed six genomic regions located on bovine Chromosomes 3, 5, 8, 15 and 27; which were significantly associated (-log10 p=4.3) with Box-Cox transformed mean FEC (BC-MFEC). DAVID analysis of the genes within the significant genomic regions suggested a correlation between our results and annotation for genes involved in inflammatory response to infection. Furthermore, ROH and selection signature analyses provided strong evidence that the genomic regions associated BC-MFEC have not been affected by local autozygosity or recent experimental selection. These findings provide useful information for parasite resistance prediction for young grazing cattle and suggest new candidate gene targets for development of disease-modifying therapies or future studies of host response to GI parasite infection. |
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Thesaurus Nal: |
cattle; genetic markers; heritability. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/139139/1/Cnpgl-2015-PlosOne-Genome-wide.pdf
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Marc: |
LEADER 02131naa a2200217 a 4500
001 2037193
005 2024-02-03
008 2015 bl uuuu u00u1 u #d
100 1 $aKIM, E. S.
245 $aGenome-wide scan of gastrointestinal nematode resistance in closed Angus population selected for minimized influence of MHC.$h[electronic resource]
260 $c2015
300 $a18 p.
520 $aGenetic markers associated with parasite indicator traits are ideal targets for study of marker assisted selection aimed at controlling infections that reduce herd use of anthelminthics. For this study, we collected gastrointestinal (GI) nematode fecal egg count (FEC) data from post-weaning animals of an Angus resource population challenged to a 26 week natural exposure on pasture. In all, data from 487 animals was collected over a 16 year period between 1992 and 2007, most of which were selected for a specific DRB1 allele to reduce the influence of potential allelic variant effects of the MHC locus. A genome-wide association study (GWAS) based on BovineSNP50 genotypes revealed six genomic regions located on bovine Chromosomes 3, 5, 8, 15 and 27; which were significantly associated (-log10 p=4.3) with Box-Cox transformed mean FEC (BC-MFEC). DAVID analysis of the genes within the significant genomic regions suggested a correlation between our results and annotation for genes involved in inflammatory response to infection. Furthermore, ROH and selection signature analyses provided strong evidence that the genomic regions associated BC-MFEC have not been affected by local autozygosity or recent experimental selection. These findings provide useful information for parasite resistance prediction for young grazing cattle and suggest new candidate gene targets for development of disease-modifying therapies or future studies of host response to GI parasite infection.
650 $acattle
650 $agenetic markers
650 $aheritability
700 1 $aSONSTEGARD, T. S.
700 1 $aSILVA, M. V. G. B.
700 1 $aGASBARRE, L. C.
700 1 $aTASSEL, C. P. V.
773 $tPLoS One$gv. 10, n. 3, : e0119380, 2015.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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Classificação |
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Registro |
Volume |
Status |
URL |
Voltar
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Registro Completo
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Biblioteca(s): |
Embrapa Milho e Sorgo. |
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Data corrente: |
16/01/1998 |
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Data da última atualização: |
13/07/2018 |
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Autoria: |
RAMALHO, M. A. P.; CRUZ, J. C. |
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Afiliação: |
JOSE CARLOS CRUZ, CNPMS. |
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Título: |
Mecanização de cultura consorciada de milho com feijão. |
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Ano de publicação: |
1984 |
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Fonte/Imprenta: |
Informe Agropecuário, Belo Horizonte, v. 10, n. 118, p. 19-24, 1984. |
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Idioma: |
Português |
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Palavras-Chave: |
Bean; Consorciacao; Maize. |
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Thesagro: |
Feijão; Mecanização; Milho; Phaseolus Vulgaris; Zea Mays. |
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Thesaurus NAL: |
intercropping; mechanization. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/46390/1/Mecanizacao-cultura.pdf
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Marc: |
LEADER 00657naa a2200241 a 4500
001 1478630
005 2018-07-13
008 1984 bl uuuu u00u1 u #d
100 1 $aRAMALHO, M. A. P.
245 $aMecanização de cultura consorciada de milho com feijão.$h[electronic resource]
260 $c1984
650 $aintercropping
650 $amechanization
650 $aFeijão
650 $aMecanização
650 $aMilho
650 $aPhaseolus Vulgaris
650 $aZea Mays
653 $aBean
653 $aConsorciacao
653 $aMaize
700 1 $aCRUZ, J. C.
773 $tInforme Agropecuário, Belo Horizonte$gv. 10, n. 118, p. 19-24, 1984.
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Registro original: |
Embrapa Milho e Sorgo (CNPMS) |
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Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
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